Do you have positive Double or Trriple screen for Downs syndrome or Trisomy 13/18 and have been advised Amniocentesis?

Answer:Get the Materniti21 test done and avoid the risks associated with Amniocentesis such as Miscarriage and Infection and preterm labour.

Materni T21 PLUS Non-Invasive Prenatal Test for Chromosomal  Abnormalities, Trisomy (Down’s Syndrome) 21, 18, 13, & Micro deletions

• Get positive or a negative result with MaterniT21and not a high or low risk score with regular Screening.

• Materni T21 is so much better than traditional Double or Triple screen and can be done any time after 10 weeks of pregnency. It is the only test in the world which gives a positive or negative result.

• It is so much better than getting an Amniocentesis done. It is a simple blood test and doesn't carry any risk of infection or miscarriage or Preterm labour

• You can be living anywhere in India we will send you the sample collection kit by post you simply go to clinic or lab near you and have a blood sample collected.

• we will take care of the shipment.

• To know the cost of Maternit21 call +91-994-817-5768

• Advantages of MAterniti 21 over Double/Triple screening

• Non Invasive: A Simple Blood Test: On Mothers Blood for foetal abnormalities.

• Testing as early as 10 weeks of pregnancy

• Confirmatory & follow up Molecular (DNA) test for “High Risk” Patients.

“The MaterniT21Plus laboratory-developed test is a non-invasive blood test to detect chromosomal abnormalities. The MaterniT21Plus test can detects an increase amount of chromosomal 21,18 and 13 materials as well as has Enhanced Sequencing capabilities to detect Trisomy’s (Down’s Syndrome) and additional Micro deletion’s that is circulating in a pregnant women blood as early as 10 weeks.”

Synapse Diagnostics Ltd.Hyderabad is Licensed by Sequenom to Offer its Materni T21 test in India

What is Downs Syndrome?

• Down syndrome is a genetic disorder caused when abnormal cell division results in extra genetic material from chromosome 21. This genetic disorder, which varies in severity, causes lifelong intellectual disability and developmental delays, and in some people it causes Major health problems.

  • Down syndrome is the most common genetic chromosomal disorder and cause of learning disabilities in children.

    • Better understanding of Down syndrome and early interventions can greatly increase the quality of life for children and adults with this disorder and help them live fulfilling lives.

What is trisomy 13?

Trisomy 13, also called Patau syndrome, is a chromosomal condition associated with severe intellectual disability and physical abnormalities in many parts of the body. Individuals with trisomy 13 often have heart defects, brain or spinal cord abnormalities, very small or poorly developed eyes (microphthalmia), extra fingers or toes, an opening in the lip (a cleft lip) with or without an opening in the roof of the mouth (a cleft palate), and weak muscle tone (hypotonia). Due to the presence of several life-threatening medical problems, many infants with trisomy 13 die within their first days or weeks of life. Only five percent to 10 percent of children with this condition live past their first year.

What is trisomy 18?

Trisomy 18, also called Edwards syndrome, is a chromosomal condition associated with abnormalities in many parts of the body. Individuals with trisomy 18 often have slow growth before birth (intrauterine growth retardation) and a low birth weight. Affected individuals may have heart defects and abnormalities of other organs that develop before birth. Other features of trisomy 18 include a small, abnormally shaped head; a small jaw and mouth; and clenched fists with overlapping fingers. Due to the presence of several life-threatening medical problems, many individuals with trisomy 18 die before birth or within their first month. Five to 10 percent of children with this condition live past their first year, and these children often have severe intellectual disability.

MICRODELETION's in pregnancy

• Clinically relevant micro deletions and micro duplications are more common than previously thought, occurring in up to 1 in 60 pregnancies, and can occur in pregnancies lacking ultrasound anomalies. The combined at-birth incidence of the 5 micro deletion syndromes covered by this screening test is approximately 1 in 1,000 (7-11), approaching the overall rate observed for Down syndrome .

  • The most common micro deletion, 22q11.2 deletion, is more common than Edwards syndrome and Patio syndrome combined, and is more common than cystic fibrosis.

    • Further, the risk for micro deletions is independent of maternal age, unlike whole chromosome aneuploidies like Trisomy 21 (Down syndrome) that are more prevalent in women of advanced maternal age.

      • For pregnant women under the age of 29, this means they are more likely to have a fetal micro deletion than fetal Down syndrome.

        • Most concerning is that these micro deletion syndromes are severe and can result in serious physical and/or intellectual impairment.